发明授权
- 专利标题: Carbon monoxide releasing molecules and uses thereof
- 专利标题(中): 一氧化碳释放分子及其用途
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申请号: US14112786申请日: 2012-04-19
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公开(公告)号: US09163044B2公开(公告)日: 2015-10-20
- 发明人: Walter Anton Blättler , Carlos J. R. C. Romão , Sandra Sofia Pereira Rodrigues , Lukas Adrian Kromer , Leo Edmond Otterbein , David John Gallo
- 申请人: Walter Anton Blättler , Carlos J. R. C. Romão , Sandra Sofia Pereira Rodrigues , Lukas Adrian Kromer , Leo Edmond Otterbein , David John Gallo
- 申请人地址: US MA Cambridge
- 专利权人: Alfama, Inc.
- 当前专利权人: Alfama, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Wolf, Greenfield & Sacks, P.C.
- 国际申请: PCT/US2012/034264 WO 20120419
- 国际公布: WO2012/145520 WO 20121026
- 主分类号: A01N55/02
- IPC分类号: A01N55/02 ; A61K31/28 ; C07F11/00
摘要:
Provided herein are novel carbon-monoxide releasing molecules (CO-RMs) of the Formula (I): and esters, amides, salts, solvates and hydrates thereof; wherein R1 and R2 are as described herein. Also provided are pharmaceutical compositions comprising these compounds, methods of their preparation, and their use in the treatment of liver disease and inflammation.
公开/授权文献
- US20140142176A1 CARBON MONOXIDE RELEASING MOLECULES AND USES THEREOF 公开/授权日:2014-05-22
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