According to the machine tool according to the present invention, a top-bottom guide is attached to a back surface of a base frame. By being guided by this top-bottom guide, the lifter moves in the top-bottom direction with respect to the base frame. A drive source which drives rotation of a top-bottom feed screw which extends parallel to the top-bottom guide is attached to a back surface of the base frame. This drive source is coupled with a bottom end of the top-bottom feed screw. As a result, compared to when the drive source is coupled with a top end of the top-bottom feed screw, the center of gravity of the machine tool can be set to a lower position. In this way, a machine tool can be increased in stability.