Invention Grant
US09125845B2 DNA vaccines, uses for unprocessed rolling circle amplification product and methods for making the same
有权
DNA疫苗,未加工的滚环扩增产物的用途及其制备方法
- Patent Title: DNA vaccines, uses for unprocessed rolling circle amplification product and methods for making the same
- Patent Title (中): DNA疫苗,未加工的滚环扩增产物的用途及其制备方法
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Application No.: US13077231Application Date: 2011-03-31
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Publication No.: US09125845B2Publication Date: 2015-09-08
- Inventor: John Richard Nelson , Nichole Lea Wood , Brian Michael Davis , Andrew Soliz Torres
- Applicant: John Richard Nelson , Nichole Lea Wood , Brian Michael Davis , Andrew Soliz Torres
- Applicant Address: US NY Niskayuna
- Assignee: General Electric Company
- Current Assignee: General Electric Company
- Current Assignee Address: US NY Niskayuna
- Agent Jenifer E. Haeckl
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; A61K39/02 ; A61K39/002 ; A61K39/145

Abstract:
A method of eliciting an immune response in an organism comprising: providing an unprocessed rolling circle amplification (RCA) product; and administering an effective amount of the unprocessed RCA product to the organism to elicit the immune response, wherein the unprocessed RCA product is prepared from a circular nucleic acid template comprising at least one promoter sequence, and at least one target sequence. A vaccine comprising unprocessed RCA product is also provided and methods for making the same.
Public/Granted literature
- US20110206728A1 DNA VACCINES, USES FOR UNPROCESSED ROLLING CIRCLE AMPLIFICATION PRODUCT AND METHODS FOR MAKING THE SAME Public/Granted day:2011-08-25
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