Invention Grant
US09125845B2 DNA vaccines, uses for unprocessed rolling circle amplification product and methods for making the same 有权
DNA疫苗,未加工的滚环扩增产物的用途及其制备方法

DNA vaccines, uses for unprocessed rolling circle amplification product and methods for making the same
Abstract:
A method of eliciting an immune response in an organism comprising: providing an unprocessed rolling circle amplification (RCA) product; and administering an effective amount of the unprocessed RCA product to the organism to elicit the immune response, wherein the unprocessed RCA product is prepared from a circular nucleic acid template comprising at least one promoter sequence, and at least one target sequence. A vaccine comprising unprocessed RCA product is also provided and methods for making the same.
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