发明授权
- 专利标题： Modified vasoactive intestinal peptides
- 专利标题（中）： 改良的血管活性肠肽
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申请号： US12857103申请日： 2010-08-16
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公开(公告)号： US09029505B2公开(公告)日： 2015-05-12
- 发明人: Homayoun Sadeghi , Suzanne Dagher , Andrew Turner
- 申请人： Homayoun Sadeghi , Suzanne Dagher , Andrew Turner
- 申请人地址： US PA Malvern
- 专利权人： Phasebio Pharmaceuticals, Inc.
- 当前专利权人： Phasebio Pharmaceuticals, Inc.
- 当前专利权人地址： US PA Malvern
- 代理机构： Cooley LLP
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K7/00 ; A61K38/04 ; C07K14/00 ; A61P3/10 ; A61P9/12 ; A61P9/00 ; A61K38/22 ; A61K38/39
摘要：
The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.
公开/授权文献
- US20110178017A1 MODIFIED VASOACTIVE INTESTINAL PEPTIDES 公开/授权日：2011-07-21
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