发明授权
- 专利标题: Synthesis of iodixanol in methanol
- 专利标题(中): 碘甲醇在甲醇中的合成
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申请号: US12621551申请日: 2009-11-19
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公开(公告)号: US08962886B2公开(公告)日: 2015-02-24
- 发明人: Hanne Jorunn H. Johnsen , Lars Terje Holmaas , Ole Magne Homestad
- 申请人: Hanne Jorunn H. Johnsen , Lars Terje Holmaas , Ole Magne Homestad
- 申请人地址: NO Oslo
- 专利权人: GE Healthcare AS
- 当前专利权人: GE Healthcare AS
- 当前专利权人地址: NO Oslo
- 主分类号: C07C233/64
- IPC分类号: C07C233/64 ; C07C231/12
摘要:
This invention relates to the synthesis of iodixanol (1,3-bis(acetamido)-N,N′-bis[3,5-bis(2,3-dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane), more specifically to the dimerisation of 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-isophthalamide with methanol as solvent.
公开/授权文献
- US20110021829A1 SYTNHESIS OF IODIXANOL IN METHANOL 公开/授权日:2011-01-27
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