发明授权
US08962573B2 Compounds targeting the cation-independent mannose 6-phosphate receptor
有权
靶向阳离子非依赖性甘露糖-6-磷酸受体的化合物
- 专利标题： Compounds targeting the cation-independent mannose 6-phosphate receptor
- 专利标题（中）： 靶向阳离子非依赖性甘露糖-6-磷酸受体的化合物
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申请号： US13380199申请日： 2010-07-02
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公开(公告)号： US08962573B2公开(公告)日： 2015-02-24
- 发明人: Marcel Garcia , Alain Morere , Magali Gary-Bobo , Martine Cerutti , Khaled El Cheikh , Ilaria Basile , Philippe Nirde
- 申请人： Marcel Garcia , Alain Morere , Magali Gary-Bobo , Martine Cerutti , Khaled El Cheikh , Ilaria Basile , Philippe Nirde
- 申请人地址： FR Paris FR Paris FR Montpellier FR Montpellier
- 专利权人： INSERM (Institut National de la Sante et de la Recherche Medicale),Centre National de la Recherche Scientifique—CNRS,Universite de Montpellier 1,Universite de Montpellier 2 Sciences et Techniques
- 当前专利权人： INSERM (Institut National de la Sante et de la Recherche Medicale),Centre National de la Recherche Scientifique—CNRS,Universite de Montpellier 1,Universite de Montpellier 2 Sciences et Techniques
- 当前专利权人地址： FR Paris FR Paris FR Montpellier FR Montpellier
- 代理机构： McAndrews, Held & Malloy Ltd.
- 优先权： EP09305647 20090703
- 国际申请： PCT/EP2010/059507 WO 20100702
- 国际公布： WO2011/000958 WO 20110106
- 主分类号： C07G3/00
- IPC分类号： C07G3/00 ; C07G11/00 ; C07H15/00 ; C07H17/00 ; A01N43/04 ; A61K31/70 ; A61K47/48
摘要：
The invention relates to conjugates of products of interest including glycoproteins, nanoparticles, and imaging agents and of compounds of the general formula (1): that target the cation-independent mannose 6-phosphate receptor with a high affinity. The invention also relates to their applications, for instance in enzyme replacement therapies.
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