发明授权
US08962319B2 Methods for testing an immune response using cultures of T cells, B cells, dendritic cells and follicular dendritic cells
有权
使用T细胞,B细胞,树突细胞和滤泡树突状细胞的培养物测试免疫应答的方法
- 专利标题: Methods for testing an immune response using cultures of T cells, B cells, dendritic cells and follicular dendritic cells
- 专利标题(中): 使用T细胞,B细胞,树突细胞和滤泡树突状细胞的培养物测试免疫应答的方法
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申请号: US13289024申请日: 2011-11-04
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公开(公告)号: US08962319B2公开(公告)日: 2015-02-24
- 发明人: William L. Warren , Donald Drake, III , Janice Moser , Inderpal Singh , Haifeng Song , Eric Mishkin , John G. Tew
- 申请人: William L. Warren , Donald Drake, III , Janice Moser , Inderpal Singh , Haifeng Song , Eric Mishkin , John G. Tew
- 申请人地址: US FL Orlando US VA Richmond
- 专利权人: Sanofi Pasteur Vaxdesign Corp.,Virginia Commonwealth University
- 当前专利权人: Sanofi Pasteur Vaxdesign Corp.,Virginia Commonwealth University
- 当前专利权人地址: US FL Orlando US VA Richmond
- 代理机构: Roylance, Abrams, Berdo & Goodman LLP
- 主分类号: C12N5/00
- IPC分类号: C12N5/00 ; C12N5/02 ; G01N33/50 ; C12N5/0781 ; C12N5/0783 ; C12N5/0784 ; C12N5/071
摘要:
The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.
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