发明授权
- 专利标题： Antibodies against ERBB3 and uses thereof
- 专利标题（中）： 针对ERBB3的抗体及其用途
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申请号： US12904492申请日： 2010-10-14
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公开(公告)号： US08961966B2公开(公告)日： 2015-02-24
- 发明人: Birgit Schoeberl , Ulrik Nielsen , Michael Feldhaus , Arumugam Muruganandam , David Buckler
- 申请人： Birgit Schoeberl , Ulrik Nielsen , Michael Feldhaus , Arumugam Muruganandam , David Buckler
- 申请人地址： US MA Cambridge
- 专利权人： Merrimack Pharmaceuticals, Inc.
- 当前专利权人： Merrimack Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Nelson Mullins Riley & Scarborough LLP
- 代理商 Jane E. Remillard, Esq.; Jill Gorny Sloper, Esq.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C07K16/28 ; C07K16/32 ; A61K31/337 ; A61K31/517 ; A61K33/24 ; A61K39/00
摘要：
The present invention provides a novel class of monoclonal antibodies which bind ErbB3 receptor and inhibits various ErbB3 functions. For example, the antibodies described herein are capable of binding to ErbB3 and inhibiting EGF-like ligand mediated phosphorylation of the receptor.
公开/授权文献
- US20110123523A1 ANTIBODIES AGAINST ERBB3 AND USES THEREOF 公开/授权日：2011-05-26
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