发明授权
- 专利标题: Nanopore and carbon nanotube based DNA sequencer
- 专利标题(中): 纳米孔和基于碳纳米管的DNA测序仪
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申请号: US12920817申请日: 2009-03-18
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公开(公告)号: US08961757B2公开(公告)日: 2015-02-24
- 发明人: Colin Nuckolls , Jinyao Tang , Stuart Lindsay , Jin He , Peiming Zhang , Kevin Reinhart
- 申请人: Colin Nuckolls , Jinyao Tang , Stuart Lindsay , Jin He , Peiming Zhang , Kevin Reinhart
- 申请人地址: US AZ Scottsdale US NY New York
- 专利权人: Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizona State University,The Trustees of Columbia University in the City of New York
- 当前专利权人: Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizona State University,The Trustees of Columbia University in the City of New York
- 当前专利权人地址: US AZ Scottsdale US NY New York
- 代理机构: Cooley LLP
- 代理商 Brian P. Hopkins; Dhruv Sud
- 国际申请: PCT/US2009/037563 WO 20090318
- 国际公布: WO2009/117517 WO 20090924
- 主分类号: G01N27/327
- IPC分类号: G01N27/327 ; C12Q1/68 ; G01N33/487
摘要:
The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon nanotube also serves as one electrode in a reading circuit. One end of the carbon nanotube is held in close proximity to a second electrode, and each end of the carbon nanotube is functionalized with flexibly-tethered chemical-recognition moieties, such that one will bind one site on the emerging polymer, and the second will bind another site in close proximity, generating an electrical signal between the two electrodes when the circuit is completed by the process of chemical recognition.
公开/授权文献
- US20110168562A1 Nanopore and Carbon Nanotube Based DNA Sequencer 公开/授权日:2011-07-14
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