A digital audio conferencing system has a fixed base station that is in communication with a far end (R.E.) system over a communication network. The base station is associated with a wireless loudspeaker and one or more wireless microphones. The base station operates to receive F.E. audio signals to be played by the wireless loudspeaker, and it operates to remove acoustic echo picked up by the wireless microphones. A first clock controlling F.E. audio signal sampling at the base station, and a second clock controlling audio signal sampling and at a wireless microphone are synchronized to one master, reference clock that controls the operation of the base station. Acoustic echo included in an audio signal picked up by a wireless microphone is removed by AEC functionality running in the base station.