Engineered demeter 5-methylcytosine DNA glyosylase with improved yield, stability and solubility

Invention Grant

US08951769B2 Engineered demeter 5-methylcytosine DNA glyosylase with improved yield, stability and solubility 有权

Title translation: 工程化的除垢剂5-甲基胞嘧啶DNA糖基化酶具有提高的产率，稳定性和溶解度

Patent Title: Engineered demeter 5-methylcytosine DNA glyosylase with improved yield, stability and solubility
Patent Title (中): 工程化的除垢剂5-甲基胞嘧啶DNA糖基化酶具有提高的产率，稳定性和溶解度
Application No.: US13265533

Application Date: 2010-04-19
Publication No.: US08951769B2

Publication Date: 2015-02-10
Inventor: Jin Hoe Huh , Robert Fischer
Applicant: Jin Hoe Huh , Robert Fischer
Applicant Address: US CA Oakland
Assignee: The Regents of the University of California
Current Assignee: The Regents of the University of California
Current Assignee Address: US CA Oakland
Agency: Kilpatrick Townsend & Stockton LLP
International Application: PCT/US2010/031623 WO 20100419
International Announcement: WO2010/123827 WO 20101028
Main IPC: C12N9/24
IPC: C12N9/24 ; C12Q1/68 ; C12N9/42

Abstract:

Improved active DEMETER polypeptides with internal deletions are provided.

Abstract(Chinese):

提供改进的具有内部缺失的活性DEMETER多肽。

Public/Granted literature

Information query

Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N9/00	酶，如连接酶（6.）；酶原；其组合物（用于清洁牙齿的含酶的制剂入A61K8/66、A61Q11/00；含酶或酶原的医药制剂入A61K38/43；含酶去污剂组合物入C11D）；制备、活化、抑制、分离或纯化酶的方法
C12N9/14	.水解酶（3.）
C12N9/24	..作用在糖基化合物上（3.2）