Invention Grant
US08889683B2 Substituted quinoxalines as inhibitors of fatty acid binding protein
有权
取代喹喔啉作为脂肪酸结合蛋白的抑制剂
- Patent Title: Substituted quinoxalines as inhibitors of fatty acid binding protein
- Patent Title (中): 取代喹喔啉作为脂肪酸结合蛋白的抑制剂
-
Application No.: US13242426Application Date: 2011-09-23
-
Publication No.: US08889683B2Publication Date: 2014-11-18
- Inventor: Clifford Cheng , Gerald W. Shipps, Jr. , Xiaohua Huang , Ying Huang , Ning Shao , Ashwin Rao , Anandan Palani , Peter Orth , Johannes H. Voigt , Robert J. Herr , Lana Michele Rossiter , Qi Zeng , Xianfeng Sun
- Applicant: Clifford Cheng , Gerald W. Shipps, Jr. , Xiaohua Huang , Ying Huang , Ning Shao , Ashwin Rao , Anandan Palani , Peter Orth , Johannes H. Voigt , Robert J. Herr , Lana Michele Rossiter , Qi Zeng , Xianfeng Sun
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Anna L. Cocuzzo; Catherine D. Fitch
- Main IPC: A61K31/498
- IPC: A61K31/498 ; C07D241/44 ; C07D401/14 ; C07D403/14 ; C07D413/06 ; C07D401/06 ; C07D403/12 ; C07D403/06
Abstract:
The present invention relates to novel quinoxaline compounds of Formula I: as Fatty Acid Binding Protein (“FABP”) inhibitors, pharmaceutical compositions comprising the quinoxaline compounds and the use of the quinoxaline compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose.
Public/Granted literature
- US20120122837A1 INHIBITORS OF FATTY ACID BINDING PROTEIN Public/Granted day:2012-05-17
Information query
IPC分类:
