Invention Grant
US08859783B2 Indirubin-3′-oxime derivatives as potent cyclin dependent kinase inhibitors
有权
靛玉红-3'-肟衍生物作为有效的细胞周期蛋白依赖性激酶抑制剂
- Patent Title: Indirubin-3′-oxime derivatives as potent cyclin dependent kinase inhibitors
- Patent Title (中): 靛玉红-3'-肟衍生物作为有效的细胞周期蛋白依赖性激酶抑制剂
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Application No.: US13576105Application Date: 2011-01-28
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Publication No.: US08859783B2Publication Date: 2014-10-14
- Inventor: Yong-Chul Kim , Jae-Il Kim , Soo-Ho Ban , Soon-Young Jeong , Soo-Jeong Choi , Jung-Eun Lee
- Applicant: Yong-Chul Kim , Jae-Il Kim , Soo-Ho Ban , Soon-Young Jeong , Soo-Jeong Choi , Jung-Eun Lee
- Applicant Address: KR Jeollanam-Do
- Assignee: Anygen Co., Ltd.
- Current Assignee: Anygen Co., Ltd.
- Current Assignee Address: KR Jeollanam-Do
- Agency: Kenyon & Kenyon LLP
- Priority: KR10-2010-0010715 20100205
- International Application: PCT/KR2011/000611 WO 20110128
- International Announcement: WO2011/096676 WO 20110811
- Main IPC: C07D209/38
- IPC: C07D209/38 ; A61K31/404 ; C07D403/04
Abstract:
The present invention relates to an indirubin-3′-oxime derivative as potent cyclin dependent kinase inhibitor with anti-cancer activity. More particularly, this invention relates to an indirubin-3′-oxime derivative as potent cyclin dependent kinase inhibitor having excellent anti-cancer activity against human lung cancer cell, human fibro sarcoma cell, human colon cancer cell, human leukemia cell, human stomach cancer cell, human nasopharyngeal cancer cell and/or human breast cancer cell.
Public/Granted literature
- US20120295948A1 INDIRUBIN-3'-OXIME DERIVATIVES AS POTENT CYCLIN DEPENDENT KINASE INHIBITORS Public/Granted day:2012-11-22
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