发明授权
US08846983B2 Method for reducing halogenobenzoic acid ester using ruthenium carbonyl complex
有权
使用钌羰基络合物还原卤代苯甲酸酯的方法
- 专利标题: Method for reducing halogenobenzoic acid ester using ruthenium carbonyl complex
- 专利标题(中): 使用钌羰基络合物还原卤代苯甲酸酯的方法
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申请号: US14100163申请日: 2013-12-09
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公开(公告)号: US08846983B2公开(公告)日: 2014-09-30
- 发明人: Kiyoto Hori , Osamu Ogata , Wataru Kuriyama
- 申请人: Takasago International Corporation
- 申请人地址: JP Tokyo
- 专利权人: Takasago International Corporation
- 当前专利权人: Takasago International Corporation
- 当前专利权人地址: JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2012-270942 20121212
- 主分类号: C07C29/149
- IPC分类号: C07C29/149 ; C07C51/60
摘要:
An object of the present invention is to provide a method for reducing a halogenobenzoic acid ester, in which dehalogenation is inhibited, by using a readily available catalyst. The method comprises reducing an ester with hydrogen gas by using an aromatic hydrocarbon as a solvent in the presence of a ruthenium complex represented by the following general formula (1): RuXY(CO)(L) (1) where X and Y represent monovalent anionic ligands, and L represents a tridentate aminodiphosphine ligand represented by the following general formula (2): where RZ1 represents an alkyl group having 1 to 4 carbon atoms, each RZ2 represents an alkyl group having 1 to 4 carbon atoms or a halogen atom, any adjacent two RZ2s may form a ring, Hal represents a halogen atom, and n represents 0 to 4.
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