发明授权
- 专利标题： Bipyridyl derivatives
- 专利标题（中）： 联吡啶衍生物
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申请号： US13808369申请日： 2011-06-07
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公开(公告)号： US08846931B2公开(公告)日： 2014-09-30
- 发明人: Guenter Hoelzemann , Dieter Dorsch , Alfred Jonczyk , Christiane Amendt , Frank Zenke
- 申请人： Guenter Hoelzemann , Dieter Dorsch , Alfred Jonczyk , Christiane Amendt , Frank Zenke
- 申请人地址： DE Darmstadt
- 专利权人： Merck Patent GmbH
- 当前专利权人： Merck Patent GmbH
- 当前专利权人地址： DE Darmstadt
- 代理机构： Millen, White, Zelano & Branigan, P.C.
- 优先权： EP10006927 20100705
- 国际申请： PCT/EP2011/002788 WO 20110607
- 国际公布： WO2012/003912 WO 20120112
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; A61K45/06 ; C07D213/74 ; A61K31/496 ; C07D471/04 ; A61K31/5377 ; A61K31/444 ; A61K31/4545
摘要：
The present invention relates to novel bipyridyl derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.
公开/授权文献
- US20130102608A1 BIPYRIDYL DERIVATIVES 公开/授权日：2013-04-25
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