发明授权
US08828996B2 Morpholine-spirocyclic piperidine amides as modulators of ion channels
有权
吗啉 - 螺环哌啶酰胺作为离子通道的调节剂
- 专利标题： Morpholine-spirocyclic piperidine amides as modulators of ion channels
- 专利标题（中）： 吗啉 - 螺环哌啶酰胺作为离子通道的调节剂
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申请号： US13418737申请日： 2012-03-13
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公开(公告)号： US08828996B2公开(公告)日： 2014-09-09
- 发明人: Sara Sabina Hadida-Ruah , Hayley Marie Binch , Michael Paul DeNinno , Lev Tyler Dewey Fanning , Bryan A. Frieman , Peter Diederik Jan Grootenhuis , Nicole Hilgraf , Pramod Joshi , Edward Adam Kallel , Mark Thomas Miller , Joseph Pontillo , Alina Silina , Urvi Jagdishbhai Sheth , Dennis James Hurley , Vijayalaksmi Arumugam
- 申请人： Sara Sabina Hadida-Ruah , Hayley Marie Binch , Michael Paul DeNinno , Lev Tyler Dewey Fanning , Bryan A. Frieman , Peter Diederik Jan Grootenhuis , Nicole Hilgraf , Pramod Joshi , Edward Adam Kallel , Mark Thomas Miller , Joseph Pontillo , Alina Silina , Urvi Jagdishbhai Sheth , Dennis James Hurley , Vijayalaksmi Arumugam
- 申请人地址： US MA Boston
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Boston
- 代理机构： Brinks Gilson & Lione
- 主分类号： C07D498/10
- IPC分类号： C07D498/10 ; A61K31/537
摘要：
The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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