发明授权
US08815839B2 Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
有权
作为单酰基甘油脂肪酶抑制剂的杂芳族和芳族哌嗪基氮杂环丁烷基酰胺
- 专利标题： Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
- 专利标题（中）： 作为单酰基甘油脂肪酶抑制剂的杂芳族和芳族哌嗪基氮杂环丁烷基酰胺
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申请号： US13784036申请日： 2013-03-04
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公开(公告)号： US08815839B2公开(公告)日： 2014-08-26
- 发明人: Kristen Chevalier , Jose Clemente , Scott L Dax , Chris Flores , Li Liu , Mark J Macielag , Mark McDonnell , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang , Bin Zhu
- 申请人： Janssen Pharmaceutica, NV
- 申请人地址： BE
- 专利权人： Janssen Pharmaceutica, NV
- 当前专利权人： Janssen Pharmaceutica, NV
- 当前专利权人地址： BE
- 代理商 Thomas J. Dodd
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/551 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D417/12
摘要：
Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, r, R2 and Z are defined herein.
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