发明授权
- 专利标题： System and method for measuring the ratio of forward-propagating to back-propagating second harmonic-generation signal, and applications thereof
- 专利标题（中）： 用于测量正向传播到后向传播的二次谐波发生信号的比率的系统和方法及其应用
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申请号： US13696150申请日： 2011-05-03
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公开(公告)号： US08812085B2公开(公告)日： 2014-08-19
- 发明人: Edward Brown, III , Xiaoxing Han
- 申请人： Edward Brown, III , Xiaoxing Han
- 申请人地址： US NY Rochester
- 专利权人： University of Rochester
- 当前专利权人： University of Rochester
- 当前专利权人地址： US NY Rochester
- 代理机构： Bond, Schoeneck & King, PLLC
- 代理商 William Greener
- 国际申请： PCT/US2011/034921 WO 20110503
- 国际公布： WO2011/140030 WO 20111110
- 主分类号： A61B6/00
- IPC分类号： A61B6/00
摘要：
A method and system that enable the measurement of a second-harmonic-generation-forward/backward (SHG F/B) ratio from an object by performing only a single image scan using via epi-imaging using an epi-detection technique. Two simultaneous SGH images (a forward propagating SHG “F” image and a back propagating SHG “B” image) are generated during the single image scan. A pinhole mirror can be used to separate the F-SHG and the B-SHG, which are detected by separate detectors.
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