Invention Grant
US08796270B2 N-[6-(1H-indazol-6-yl)imidazo[1,2-A]pyridin-8-yl]-6-(morpholin-4-yl)pyridazin-3-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
有权
N- [6-（1H-吲唑-6-基）咪唑并[1,2-A]吡啶-8-基] -6-（吗啉-4-基）哒嗪-3-胺或其药学上可接受的盐 ，作为SYK抑制剂
![N-[6-(1H-indazol-6-yl)imidazo[1,2-A]pyridin-8-yl]-6-(morpholin-4-yl)pyridazin-3-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor](/docs/US/2014-08-05/US08796270B2/abs.jpg.600x600.jpg)
- Patent Title: N-[6-(1H-indazol-6-yl)imidazo[1,2-A]pyridin-8-yl]-6-(morpholin-4-yl)pyridazin-3-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
- Patent Title (中): N- [6-（1H-吲唑-6-基）咪唑并[1,2-A]吡啶-8-基] -6-（吗啉-4-基）哒嗪-3-胺或其药学上可接受的盐 ，作为SYK抑制剂
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Application No.: US13862147Application Date: 2013-04-12
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Publication No.: US08796270B2Publication Date: 2014-08-05
- Inventor: Scott A. Mitchell
- Applicant: Gilead Connecticut, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Connecticut, Inc.
- Current Assignee: Gilead Connecticut, Inc.
- Current Assignee Address: US CA Foster City
- Agency: Morrison & Foerster LLP
- Main IPC: A61K31/495
- IPC: A61K31/495
![N-[6-(1H-indazol-6-yl)imidazo[1,2-A]pyridin-8-yl]-6-(morpholin-4-yl)pyridazin-3-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor](/abs-image/US/2014/08/05/US08796270B2/abs.jpg.150x150.jpg)
Abstract:
An imidazopyridine having the structure or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.
Public/Granted literature
- US20130231330A1 IMIDAZOPYRIZINE SYK INHIBITORS Public/Granted day:2013-09-05
Information query
