Invention Grant
US08796258B2 Cyclic azabenzimidazole derivatives useful as anti-diabetic agents
有权
用作抗糖尿病药的环状氮杂苯并咪唑衍生物
- Patent Title: Cyclic azabenzimidazole derivatives useful as anti-diabetic agents
- Patent Title (中): 用作抗糖尿病药的环状氮杂苯并咪唑衍生物
-
Application No.: US13812536Application Date: 2012-02-23
-
Publication No.: US08796258B2Publication Date: 2014-08-05
- Inventor: Rajan Anand , James M. Apgar , Tesfaye Biftu , Ping Chen , Lin Chu , Vincent J. Colandrea , Guizhen Dong , James F. Dropinski , Danqing Feng , Jacqueline D. Hicks , Jinlong Jiang , Alexander J. Kim , Kenneth J. Leavitt , Bing Li , Xiaoxia Qian , Iyassu Sebhat , Lan Wei , Robert R. Wilkening , Zhicai Wu
- Applicant: Rajan Anand , James M. Apgar , Tesfaye Biftu , Ping Chen , Lin Chu , Vincent J. Colandrea , Guizhen Dong , James F. Dropinski , Danqing Feng , Jacqueline D. Hicks , Jinlong Jiang , Alexander J. Kim , Kenneth J. Leavitt , Bing Li , Xiaoxia Qian , Iyassu Sebhat , Lan Wei , Robert R. Wilkening , Zhicai Wu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Baerbel R. Brown; Catherine D. Fitch
- International Application: PCT/US2012/026261 WO 20120223
- International Announcement: WO2012/116145 WO 20120830
- Main IPC: A61K31/00
- IPC: A61K31/00 ; C07D513/02
Abstract:
Novel compounds of structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
Public/Granted literature
- US20130123237A1 NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS Public/Granted day:2013-05-16
Information query
