发明授权
- 专利标题: Drug carrier with chelating complex micelles and the application thereof
- 专利标题(中): 具有螯合复合胶束的药物载体及其应用
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申请号: US13683482申请日: 2012-11-21
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公开(公告)号: US08785569B2公开(公告)日: 2014-07-22
- 发明人: Chau-Hui Wang , Chia-Hung Chen , Johnson Lin , Jing-Yi Chen , Wei-Chuan Liao
- 申请人: Original Biomedicals, Co., Ltd.
- 申请人地址: TW Tainan
- 专利权人: Original Biomedicals Co., Ltd.
- 当前专利权人: Original Biomedicals Co., Ltd.
- 当前专利权人地址: TW Tainan
- 代理机构: WPAT, PC
- 代理商 Justin King
- 优先权: TW101128939A 20120810
- 主分类号: C08G81/00
- IPC分类号: C08G81/00 ; A61K9/51 ; A61K9/107 ; A61K31/00 ; A61K33/24 ; A61K47/48 ; A61P35/00
摘要:
This invention provides Chelating Complex Micelles as a drug carrier. The Chelating Complex Micelles can load drugs without changing their structure, and therefore extend the half-life of drugs in the human body. The chelating complex micelles contain a metal ion core, at least one polymer, and at least one drug molecule. The metal ion is considered as a Lewis acid while polymer chain and drug molecules are referred to as Lewis bases. The drug molecule is linked to the polymer via forming coordinate bonds with metal ion, and then self-assembled to form chelating complex micelles as a drug carrier.
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