Invention Grant
- Patent Title: Alkoxy pyrimidine PDE10 inhibitors
- Patent Title (中): 烷氧基嘧啶PDE10抑制剂
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Application No.: US13820648Application Date: 2011-09-26
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Publication No.: US08785467B2Publication Date: 2014-07-22
- Inventor: Christopher D. Cox , Izzat T. Raheem , William D. Shipe , Cory R. Theberge
- Applicant: Christopher D. Cox , Izzat T. Raheem , William D. Shipe , Cory R. Theberge
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Sylvia A. Ayler; John C. Todaro
- International Application: PCT/US2011/053194 WO 20110926
- International Announcement: WO2012/044561 WO 20120405
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; A61K31/506 ; C07D239/30 ; C07D239/48 ; C07D239/52 ; C07D239/56
Abstract:
The present invention is directed to 2-alkoxy pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
Public/Granted literature
- US20130158056A1 ALKOXY PYRIMIDINE PDE10 INHIBITORS Public/Granted day:2013-06-20
Information query
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