A laser diode drive circuit includes a power supply circuit connected to an anode of a laser diode to supply a variable voltage to the laser diode, and a drive current control circuit connected to a cathode of the laser diode to control a current of the laser diode. The power supply circuit generates a start-up voltage which is equal to the sum of the maximum drive voltage that is larger than the drive voltage and a predetermined first reference voltage, acquires a cathode voltage of the laser diode while the start-up voltage is generated, generates a voltage by lowering from the start-up voltage so as to diminish the difference between the acquired cathode voltage and the first reference voltage, and the first reference voltage is the minimum cathode voltage necessary to supply a predetermined current to the laser diode by the drive current control circuit.