发明授权
- 专利标题: Trehalose compound, method for producing same, and pharmaceutical product containing the compound
- 专利标题(中): 海藻糖化合物,其制造方法以及含有该化合物的药物
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申请号: US13126842申请日: 2009-10-27
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公开(公告)号: US08741871B2公开(公告)日: 2014-06-03
- 发明人: Mugio Nishizawa , Hiroshi Imagawa , Hirofumi Yamamoto , Jun Sakurai , Masataka Oda
- 申请人: Mugio Nishizawa , Hiroshi Imagawa , Hirofumi Yamamoto , Jun Sakurai , Masataka Oda , Reiko Nishizawa
- 申请人地址: JP Kyoto
- 专利权人: Glytech, Inc.
- 当前专利权人: Glytech, Inc.
- 当前专利权人地址: JP Kyoto
- 代理机构: Osha Liang LLP
- 优先权: JP2008-282613 20081031; JP2009-046824 20090227
- 国际申请: PCT/JP2009/005650 WO 20091027
- 国际公布: WO2010/050178 WO 20100506
- 主分类号: A61K31/7024
- IPC分类号: A61K31/7024 ; C07H13/06 ; C07H13/08
摘要:
A trehalose compound having high immunopotentiating activity and low toxicity is represented by formula (1). (In the formula, X and X′ each represents a phenyl, a naphthyl, R1—CHR1— (wherein R1 and R2 each represents a C7-C21 alkyl group or the like) or the like; and n and n′ each independently represents an integer of 0-3). The compound exhibits a high activating effect on macrophages and neutrophils.
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