发明授权
US08712499B2 Quantitative oxygen imaging systems and methods using echo-based single point imaging
有权
定量氧成像系统和使用基于回波的单点成像的方法
- 专利标题: Quantitative oxygen imaging systems and methods using echo-based single point imaging
- 专利标题(中): 定量氧成像系统和使用基于回波的单点成像的方法
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申请号: US13131165申请日: 2009-11-25
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公开(公告)号: US08712499B2公开(公告)日: 2014-04-29
- 发明人: Sankaran Subramanian , Nallathamby Devasahayam , Shingo Matsumoto , James B. Mitchell , Murali Krishna Cherukuri , John A. Cook
- 申请人: Sankaran Subramanian , Nallathamby Devasahayam , Shingo Matsumoto , James B. Mitchell , Murali Krishna Cherukuri , John A. Cook
- 申请人地址: US DC Washington
- 专利权人: The United States of America as represented by the Secretary, Department of Health and Human Services
- 当前专利权人: The United States of America as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址: US DC Washington
- 代理机构: Polsinelli PC
- 代理商 Teddy C. Scott, Jr.; Ron Galant
- 国际申请: PCT/US2009/065956 WO 20091125
- 国际公布: WO2010/062973 WO 20100603
- 主分类号: A61B5/055
- IPC分类号: A61B5/055
摘要:
An echo-based single point imaging (ESPI) system (10) providing high-resolution oxygen images of a sample is disclosed. The ESPI system (10) employs spin echo detection of the resonance from a spin probe and concurrent Single Point Imaging (SPI) for spatial encoding of the oxygen concentration within the sample. Images are derived by comparing spin echo intensities of two images reconstructed at two time points selected at identical time intervals on either side of a refocusing pulse, eliminating artifacts associated with sample magnetic susceptibility and field inhomogeneity effects.
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