发明授权
US08673302B2 Anti-cMet antibody and its use for the detection and the diagnosis of cancer
有权
抗cMet抗体及其用于检测和诊断癌症的用途
- 专利标题: Anti-cMet antibody and its use for the detection and the diagnosis of cancer
- 专利标题(中): 抗cMet抗体及其用于检测和诊断癌症的用途
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申请号: US13391435申请日: 2010-08-23
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公开(公告)号: US08673302B2公开(公告)日: 2014-03-18
- 发明人: Liliane Goetsch , Alexandra Jouhanneaud
- 申请人: Liliane Goetsch , Alexandra Jouhanneaud
- 申请人地址: FR Boulogne-Billancourt
- 专利权人: Pierre Fabre Medicament
- 当前专利权人: Pierre Fabre Medicament
- 当前专利权人地址: FR Boulogne-Billancourt
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 优先权: EP09305777 20090821
- 国际申请: PCT/EP2010/062271 WO 20100823
- 国际公布: WO2011/020925 WO 20110224
- 主分类号: A61K38/00
- IPC分类号: A61K38/00
摘要:
The present invention relates to the field of prognosis and/or diagnosis of a proliferative disease in a patient. More particularly, the invention relates to antibodies capable of binding to the human cMet receptor, as well as the amino acid and nucleic acid sequences coding for these antibodies. The invention likewise comprises the use of said antibodies, and corresponding processes, for detecting and diagnosing pathological hyperproliterative oncogenic disorders associated with expression of cMet. In certain embodiments, the disorders are oncogenic disorders associated with increased expression of cMet polypeptide relative to normal or any other pathology connected with the overexpression of cMet. The invention finally comprises products and/or compositions or kits comprising at least such antibodies for the prognosis or diagnostic of certain cancers.
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