Invention Grant
US08669361B2 Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use
有权
吡唑-4-基 - 杂环基甲酰胺化合物及其使用方法
- Patent Title: Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use
- Patent Title (中): 吡唑-4-基 - 杂环基甲酰胺化合物及其使用方法
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Application No.: US13834316Application Date: 2013-03-15
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Publication No.: US08669361B2Publication Date: 2014-03-11
- Inventor: Xiaojing Wang
- Applicant: Genentech, Inc.
- Applicant Address: CH Basel
- Assignee: F. Hoffmann-La Roche AG
- Current Assignee: F. Hoffmann-La Roche AG
- Current Assignee Address: CH Basel
- Agency: Genentech, Inc.
- Agent Alex Andrus
- Main IPC: C07D239/00
- IPC: C07D239/00

Abstract:
Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is a thiazolyl, picolinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Public/Granted literature
- US20130203732A1 PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE Public/Granted day:2013-08-08
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