发明授权
US08637645B2 H5 subtype-specific binding proteins useful for H5 avian influenza diagnosis and surveillance
有权
H5亚型特异性结合蛋白可用于H5禽流感诊断和监测
- 专利标题： H5 subtype-specific binding proteins useful for H5 avian influenza diagnosis and surveillance
- 专利标题（中）： H5亚型特异性结合蛋白可用于H5禽流感诊断和监测
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申请号： US13613813申请日： 2012-09-13
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公开(公告)号： US08637645B2公开(公告)日： 2014-01-28
- 发明人: Yuen Fern Ho , Qing Yun Du , Fang He , Jimmy Hwei-Sing Kwang
- 申请人： Yuen Fern Ho , Qing Yun Du , Fang He , Jimmy Hwei-Sing Kwang
- 申请人地址： SG Singapore
- 专利权人： Temasek Life Sciences Laboratory Limited
- 当前专利权人： Temasek Life Sciences Laboratory Limited
- 当前专利权人地址： SG Singapore
- 代理机构： Rothwell, Figg, Ernst & Manbeck P.C.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12Q1/70 ; C07K16/10 ; C12N7/00 ; G01N21/64 ; G01N33/569 ; G01N33/577 ; A61K39/145 ; A61K39/42
摘要：
The invention provides monoclonal antibodies and related binding proteins that bind specifically to the envelope glycoprotein of H5 subtypes of avian influenza virus (“AIV”). The monoclonal antibodies and related binding proteins are useful for the detection of H5 subtypes of AIV, including the pathogenic H5N1 subtypes. Virus may be detected in formalin preserved, paraffin embedded specimens as well as frozen specimens and biological fluids. Accordingly, the invention provides for the diagnosis and surveillance of dangerous viral infections.
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