发明授权
- 专利标题: NMR, MRI, and spectroscopic MRI in inhomogeneous fields
- 专利标题(中): NMR,MRI和光谱MRI在不均匀的领域
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申请号: US11917639申请日: 2006-06-16
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公开(公告)号: US08614575B2公开(公告)日: 2013-12-24
- 发明人: Vasiliki Demas , Alexander Pines , Rachel W. Martin , John Franck , Jeffrey A. Reimer
- 申请人: Vasiliki Demas , Alexander Pines , Rachel W. Martin , John Franck , Jeffrey A. Reimer
- 申请人地址: US CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: US CA Oakland
- 代理机构: Lawrence Berkeley National Laboratory
- 国际申请: PCT/US2006/023787 WO 20060616
- 国际公布: WO2008/024092 WO 20080228
- 主分类号: G01V3/00
- IPC分类号: G01V3/00
摘要:
A method for locally creating effectively homogeneous or “clean” magnetic field gradients (of high uniformity) for imaging (with NMR, MRI, or spectroscopic MRI) both in in-situ and ex-situ systems with high degrees of inhomogeneous field strength. The method of imaging comprises: a) providing a functional approximation of an inhomogeneous static magnetic field strength B0({right arrow over (r)}) at a spatial position {right arrow over (r)}; b) providing a temporal functional approximation of {right arrow over (G)}shim(t) with i basis functions and j variables for each basis function, resulting in vij variables; c) providing a measured value Ω, which is an temporally accumulated dephasing due to the inhomogeneities of B0({right arrow over (r)}); and d) minimizing a difference in the local dephasing angle φ({right arrow over (r)},t)=γ∫0t√{square root over (|{right arrow over (B)}1({right arrow over (r)},t′)|2+({right arrow over (r)}·{right arrow over (G)}shimGshim(t′)+∥{right arrow over (B)}0({right arrow over (r)})∥Δω({right arrow over (r)},t′)/γ)2)}dt′−Ω by varying the vij variables to form a set of minimized vij variables. The method requires calibration of the static fields prior to minimization, but may thereafter be implemented without such calibration, may be used in open or closed systems, and potentially portable systems.
公开/授权文献
- US20100102811A1 NMR, MRI, and Spectroscopic MRI in Inhomogeneous Fields 公开/授权日:2010-04-29
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