发明授权
US08614575B2 NMR, MRI, and spectroscopic MRI in inhomogeneous fields 有权
NMR,MRI和光谱MRI在不均匀的领域

NMR, MRI, and spectroscopic MRI in inhomogeneous fields
摘要:
A method for locally creating effectively homogeneous or “clean” magnetic field gradients (of high uniformity) for imaging (with NMR, MRI, or spectroscopic MRI) both in in-situ and ex-situ systems with high degrees of inhomogeneous field strength. The method of imaging comprises: a) providing a functional approximation of an inhomogeneous static magnetic field strength B0({right arrow over (r)}) at a spatial position {right arrow over (r)}; b) providing a temporal functional approximation of {right arrow over (G)}shim(t) with i basis functions and j variables for each basis function, resulting in vij variables; c) providing a measured value Ω, which is an temporally accumulated dephasing due to the inhomogeneities of B0({right arrow over (r)}); and d) minimizing a difference in the local dephasing angle φ({right arrow over (r)},t)=γ∫0t√{square root over (|{right arrow over (B)}1({right arrow over (r)},t′)|2+({right arrow over (r)}·{right arrow over (G)}shimGshim(t′)+∥{right arrow over (B)}0({right arrow over (r)})∥Δω({right arrow over (r)},t′)/γ)2)}dt′−Ω by varying the vij variables to form a set of minimized vij variables. The method requires calibration of the static fields prior to minimization, but may thereafter be implemented without such calibration, may be used in open or closed systems, and potentially portable systems.
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