- 专利标题: Immunogenic peptides and methods of use for treating and preventing cancer
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申请号: US12966341申请日: 2010-12-13
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公开(公告)号: US08614304B2公开(公告)日: 2013-12-24
- 发明人: Jay A. Berzofsky , Leon T. Van den Broeke , Crystal Mackall , Lee J. Helman
- 申请人: Jay A. Berzofsky , Leon T. Van den Broeke , Crystal Mackall , Lee J. Helman
- 申请人地址: US DC Washington
- 专利权人: The United States of America, as represented by the Secretary, Department of Health and Human Serives
- 当前专利权人: The United States of America, as represented by the Secretary, Department of Health and Human Serives
- 当前专利权人地址: US DC Washington
- 代理机构: Leydig, Voit & Mayer
- 主分类号: C07H21/02
- IPC分类号: C07H21/02
摘要:
Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are pharmaceutical compositions, vaccines for use in the treatment or prevention of cancer, e.g., alveolar rhabodomyosarcoma, methods of stimulating a T cell to kill a tumor cell, methods of stimulating CD4+ and CD8+ T cells, and methods of treating or preventing cancer are further provided herein.
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