Systems and methods based on firing table fitting allow interception of a small low-altitude low-velocity target. A system includes: a target detecting system, a directing control system, a launch control system, an interception execution system, a communication bus a, a communication bus b and a communication bus c. Firing table data under a standard working condition and fitting parameters under different working conditions are pre-stored in the system. Based on target flight data and environment condition parameters, a lead aiming point is predicted, a time sequence of each stage of a fight flow is controlled, and firing data are output to execute an interception by the launch control system. An interception operation is simplified, a ground control of a non-controlled bomb fight flow is realized, a single shot success probability of an interception system is increased, and an interception cost is reduced.