发明授权
- 专利标题： Nicotine immunonanotherapeutics
- 专利标题（中）： 尼古丁免疫治疗
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申请号： US12428388申请日： 2009-04-22
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公开(公告)号： US08591905B2公开(公告)日： 2013-11-26
- 发明人: Ulrich von Andrian , Omid C. Farokhzad , Frank Alexis , Matteo Iannacone , Pamela Basto , Jinjun Shi , Elliott Ashley Moseman , Robert S. Langer , Elena Tonti
- 申请人： Ulrich von Andrian , Omid C. Farokhzad , Frank Alexis , Matteo Iannacone , Pamela Basto , Jinjun Shi , Elliott Ashley Moseman , Robert S. Langer , Elena Tonti
- 申请人地址： US MA Boston US MA Cambridge US MA Cambridge
- 专利权人： The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College,Massachusetts Institute of Technology
- 当前专利权人： The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College,Massachusetts Institute of Technology
- 当前专利权人地址： US MA Boston US MA Cambridge US MA Cambridge
- 代理机构： Pabst Patent Group LLP
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K47/00
摘要：
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. For example, the present invention nanocarriers capable of eliciting an immune response and the production of anti-nicotine antibodies.
公开/授权文献
- US20100092425A1 Nicotine Immunonanotherapeutics 公开/授权日：2010-04-15
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