Provided are an endoscopic diagnosis support method, an endoscopic diagnosis support apparatus, and an endoscopic diagnosis support program, all of which are capable of extracting an image picking up a bleeding region easily and accurately from among a large number of endoscopic images picked up by an endoscope observation apparatus by calculating a tone from a color signal of each of plural image zones obtained by dividing the endoscopic image; and discerning an image zone including a bleeding region by judging a difference among each of the plural image zones based on a tone of the calculated each image zone in the endoscopic diagnosis support apparatus for supporting an endoscopic diagnosis performed based on an endoscopic image picked up by an endoscope observation apparatus.