Invention Grant
- Patent Title: Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
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Application No.: US12631404Application Date: 2009-12-04
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Publication No.: US08563735B2Publication Date: 2013-10-22
- Inventor: Milan Bruncko , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa Hasvold , Laura Hexamer , Aaron Kunzer , Robert A. Mantei , William J. McClellan , Chang H. Park , Cheol-Min Park , Andrew M. Petros , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt
- Applicant: Milan Bruncko , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa Hasvold , Laura Hexamer , Aaron Kunzer , Robert A. Mantei , William J. McClellan , Chang H. Park , Cheol-Min Park , Andrew M. Petros , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt
- Applicant Address: US IL North Chicago
- Assignee: Abbvie Inc.
- Current Assignee: Abbvie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Jones Day
- Main IPC: C07D401/10
- IPC: C07D401/10 ; C07D213/62 ; C07D307/02
Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.
Public/Granted literature
- US20100152183A1 BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES Public/Granted day:2010-06-17
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