A method operates a clutch release system of a vehicle having an electrically actuable clutch release unit including a sensor for detecting a position of a release piston, a control unit for controlling the release piston as a function of a detected position of a clutch actuating device, and a sensor for detecting the position of the clutch actuating device. A characteristic curve function describes a relationship between the position of the clutch actuating device and the position of the release piston. The function is taken into consideration during actuation of the clutch release system to obtain a consistent clutch release at a defined position of the clutch actuating device despite progressive wear of the clutch release system.