发明授权
- 专利标题： VHNAR anti-cytokine domains
- 专利标题（中）： VHNAR抗细胞因子结构域
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申请号： US12939195申请日： 2010-11-04
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公开(公告)号： US08496933B2公开(公告)日： 2013-07-30
- 发明人: Jorge F. Paniagua-Solís , María Teresa Mata-González , Walter J. García-Ubbelohde , Araceli Olguín-Jimenez , Alexei F. Licea-Navarro , Tanya A. Camacho-Villegas , Edna Sanchez-Castrejon
- 申请人： Jorge F. Paniagua-Solís , María Teresa Mata-González , Walter J. García-Ubbelohde , Araceli Olguín-Jimenez , Alexei F. Licea-Navarro , Tanya A. Camacho-Villegas , Edna Sanchez-Castrejon
- 申请人地址： MX Delegacion Benito Juarez
- 专利权人： Laboratorios Silanes, S.A. de C.V.
- 当前专利权人： Laboratorios Silanes, S.A. de C.V.
- 当前专利权人地址： MX Delegacion Benito Juarez
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K38/16 ; C07K16/22
摘要：
The present invention concerns therapeutic compositions containing proteins that are the variable regions of IgNAR immunoglobulins, denominated vNAR, that specifically bind and neutralizes cytokines involved in a diversity of process such as inflammation and neovascularization, its ability to reach, bind, and neutralize the activity of one antigenic molecule localized in an immunoprivileged organs, are also described.
公开/授权文献
- US20110129473A1 VHNAR ANTI-CYTOKINE DOMAINS 公开/授权日：2011-06-02
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