A method and apparatus are set forth for controlling and actuator in a moving web manufacturing process. The method includes: (1) measuring a plurality of actuator profiles and in response generating nominal response models thereof; (2) generating a multivariable profile prediction based on the nominal response models; (3) generating a multivariable control target based at least one of the actuator profile; and (4) adjusting control of the actuator by minimizing error between the multivariable control target and the multivariable profile prediction.