发明授权
- 专利标题： Triazole compounds that modulate Hsp90 activity
- 专利标题（中）： 三唑化合物调节Hsp90活性
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申请号： US13333191申请日： 2011-12-21
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公开(公告)号： US08486932B2公开(公告)日： 2013-07-16
- 发明人: Joseph A. Burlison , Shijie Zhang , Weiwen Ying , Dinesh U. Chimmanamada , Minghu Song , Junghyun Chae , Stefan Schweizer
- 申请人： Joseph A. Burlison , Shijie Zhang , Weiwen Ying , Dinesh U. Chimmanamada , Minghu Song , Junghyun Chae , Stefan Schweizer
- 申请人地址： US MA Lexington
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人地址： US MA Lexington
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis
- 主分类号： A61K31/41
- IPC分类号： A61K31/41 ; C07D249/00
摘要：
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a pharmaceutical composition comprising such a compound.
公开/授权文献
- US20120101072A1 TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY 公开/授权日：2012-04-26
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