- 专利标题： Substituted hydroxamic acids and uses thereof
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申请号： US13217401申请日： 2011-08-25
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公开(公告)号： US08471026B2公开(公告)日： 2013-06-25
- 发明人: Christopher Blackburn , Kenneth M. Gigstad , He Xu
- 申请人： Christopher Blackburn , Kenneth M. Gigstad , He Xu
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Millennium Pharmaceuticals, Inc.
- 主分类号： C07D471/02
- IPC分类号： C07D471/02 ; A61K31/44
摘要：
This invention provides compounds of formula (I): wherein R1a, R1b, R1c, R1d, R2a, R2b, X1, X2, and G have values as described in the specification, useful as inhibitors of HDAC6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders.
公开/授权文献
- US20120053201A1 SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF 公开/授权日：2012-03-01
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