One embodiment relates to a computer-implemented method for detecting malware-infected electronic mail messages. A server computer monitors an email account which is associated with a unique email address for receipt of an email message, the unique email address being associated with a unique contact in an address book on a client computer. The server computer determines that an email message addressed to the unique email address has been received and performs automated analysis to confirm that the email message contains malware. Other embodiments, aspects and features are also disclosed.