发明授权
US08440668B2 Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment of type 2 diabetes
有权
β-氨基杂环二肽基肽酶抑制剂用于治疗2型糖尿病
- 专利标题： Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment of type 2 diabetes
- 专利标题（中）： β-氨基杂环二肽基肽酶抑制剂用于治疗2型糖尿病
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申请号： US13086563申请日： 2011-04-14
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公开(公告)号： US08440668B2公开(公告)日： 2013-05-14
- 发明人: Scott D. Edmondson , Michael Fisher , Dooseop Kim , Malcolm MacCoss , Emma R. Parmee , Ann E. Weber , Jinyou Xu
- 申请人： Scott D. Edmondson , Michael Fisher , Dooseop Kim , Malcolm MacCoss , Emma R. Parmee , Ann E. Weber , Jinyou Xu
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp
- 当前专利权人： Merck Sharp & Dohme Corp
- 当前专利权人地址： US NJ Rahway
- 代理商 Baerbel R. Brown; John C. Todaro
- 主分类号： A61K31/495
- IPC分类号： A61K31/495 ; A61K31/40
摘要：
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
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