Invention Grant
- Patent Title: 2-aminopyridine derivatives as glucokinase activators
- Patent Title (中): 2-氨基吡啶衍生物作为葡糖激酶活化剂
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Application No.: US12524327Application Date: 2008-01-16
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Publication No.: US08431713B2Publication Date: 2013-04-30
- Inventor: Thomas Daniel Aicher , Steven Armen Boyd , Mark Joseph Chicarelli , Kevin Ronald Condroski , Rustam Ferdinand Garrey , Ronald Jay Hinklin , Ajay Singh , Timothy M. Turner
- Applicant: Thomas Daniel Aicher , Steven Armen Boyd , Mark Joseph Chicarelli , Kevin Ronald Condroski , Rustam Ferdinand Garrey , Ronald Jay Hinklin , Ajay Singh , Timothy M. Turner
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma, Inc.
- Current Assignee: Array BioPharma, Inc.
- Current Assignee Address: US CO Boulder
- Agency: Banner & Witcoff, Ltd.
- International Application: PCT/US2008/051194 WO 20080116
- International Announcement: WO2008/091770 WO 20080731
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D213/55
Abstract:
Provided are compounds having the Formula I or salts thereof, wherein R2, L, R3, R11, D2 and R13 are as defined herein, that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes mellitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase.
Public/Granted literature
- US20100099713A1 2-AMINOPYRIDINE DERIVATIVES AS GLUCOKINASE ACTIVATORS Public/Granted day:2010-04-22
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