Systems and methods for testing uniform resource identifier protocols, comprising a fuzzer that can accept an input, and produce a fuzzed uniform resource identifier (URI), and a debugger that monitors effects of invoking the fuzzed uniform resource identifier. The input can comprise a directory containing a plurality of valid uniform resource identifier bodies, which can be fuzzed and invoked. The debugger can monitor a target application as well as other applications and/or processes affected by the uniform resource identifier as invoked.