System and methods are provided for configuring operation of a remote control by a display device. In one embodiment a method includes detecting user selection of an input of the display device and determining a command for the remote control based on the user selection of the input, wherein the command identifies a configuration for the remote control. The method further includes transmitting the command to the remote control, by the display device, for configuration of the remote control, wherein the configuration specifies operation of the remote control with one or more devices associated with the input.