发明授权
- 专利标题: Process for preparing 1-phenylpyrazoles
- 专利标题(中): 1-苯基吡唑的制备方法
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申请号: US13393624申请日: 2010-09-03
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公开(公告)号: US08362271B2公开(公告)日: 2013-01-29
- 发明人: Maximilian Dochnahl , Gunter Lipowsky
- 申请人: Maximilian Dochnahl , Gunter Lipowsky
- 申请人地址: DE Ludwigshafen
- 专利权人: BASF SE
- 当前专利权人: BASF SE
- 当前专利权人地址: DE Ludwigshafen
- 代理机构: Brinks Hofer Gilson & Lione
- 优先权: EP09169528 20090904
- 国际申请: PCT/EP2010/062950 WO 20100903
- 国际公布: WO2011/026937 WO 20110310
- 主分类号: C07D231/10
- IPC分类号: C07D231/10
摘要:
The present invention to a process for preparing 1-phenylpyrazoles of the formula I in which each R1 is independently selected from chlorine, fluorine, alkyl, haloalkyl, alkoxy and haloalkoxy; n is 1, 2 or 3; each R2 is independently selected from cyano, nitro, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio and alkoxycarbonyl; m is 0, 1 or 2; A is alkyl, aryl or aryl-C1-C4-alkyl, where A optionally bears 1, 2, 3 or 4 substituents comprising reacting a phenyl halide of the formula (II) with apyrazole derivative of the formula (III) in which X is chlorine, iodine or bromine; and R1, n, R2, m and A are each as defined above, in the presence of a base and a catalytic system comprising a ligand and a metal compound selected from palladium compounds, iron compounds and copper compounds.
公开/授权文献
- US20120165544A1 Process for Preparing 1-Phenylpyrazoles 公开/授权日:2012-06-28
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