- 专利标题： Triazole compounds that modulate HSP90 activity
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申请号： US12815322申请日： 2010-06-14
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公开(公告)号： US08362055B2公开(公告)日： 2013-01-29
- 发明人: Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh U. Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard P. Ng , Kevin Foley , Zhenjian Du , James Barsoum
- 申请人： Weiwen Ying , David James , Shijie Zhang , Teresa Przewloka , Junghyun Chae , Dinesh U. Chimmanamada , Chi-Wan Lee , Elena Kostik , Howard P. Ng , Kevin Foley , Zhenjian Du , James Barsoum
- 申请人地址： US MA Lexington
- 专利权人： Synta Pharmaceuticals, Inc.
- 当前专利权人： Synta Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Lexington
- 代理机构： McCarter & English LLP
- 代理商 Steven G. Davis
- 主分类号： A61K31/41
- IPC分类号： A61K31/41 ; C07D249/08
摘要：
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- US20110105749A1 TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY 公开/授权日：2011-05-05
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