发明授权
- 专利标题: Primary amine diazeniumdiolate heterocyclic derivatives
- 专利标题(中): 伯胺二氮烯鎓二醇杂环衍生物
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申请号: US13412032申请日: 2012-03-05
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公开(公告)号: US08361994B2公开(公告)日: 2013-01-29
- 发明人: Amjad Ali , Michael Man-Chu Lo , Zhiqiang Guo , Brent Whitehead , Timothy J. Henderson , Lin Yan , Shrenik K. Shah
- 申请人: Amjad Ali , Michael Man-Chu Lo , Zhiqiang Guo , Brent Whitehead , Timothy J. Henderson , Lin Yan , Shrenik K. Shah
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp
- 当前专利权人: Merck Sharp & Dohme Corp
- 当前专利权人地址: US NJ Rahway
- 代理商 Richard S. Parr; Catherine D. Fitch
- 主分类号: C07D205/04
- IPC分类号: C07D205/04 ; C07D207/12 ; C07D211/44 ; C07D309/10 ; C07D401/02 ; C07D401/04 ; C07D401/14 ; C07D403/02 ; A61K31/655 ; A61P9/12
摘要:
A compound having the structure useful for treating hypertension, Pulmonary Arterial Hypertension (PAH), congestive heart failure, conditions resulting from excessive water retention, cardiovascular disease, diabetes, oxidative stress, endothelial dysfunction, cirrhosis, pre-eclampsia, osteoporosis or nephropathy.
公开/授权文献
- US20120232039A1 PRIMARY AMINE DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES 公开/授权日:2012-09-13
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