- 专利标题： Compounds for enzyme inhibition
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申请号： US13328909申请日： 2011-12-16
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公开(公告)号： US08357683B2公开(公告)日： 2013-01-22
- 发明人: Kevin D. Shenk , Francesco Parlati , Han-jie Zhou , Catherine Sylvain , Mark S. Smyth , Mark K. Bennett , Guy J. Laidig
- 申请人： Kevin D. Shenk , Francesco Parlati , Han-jie Zhou , Catherine Sylvain , Mark S. Smyth , Mark K. Bennett , Guy J. Laidig
- 申请人地址： US CA South San Francisco
- 专利权人： Onyx Therapeutics, Inc.
- 当前专利权人： Onyx Therapeutics, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Fish & Richardson P.C.
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/427 ; A61K31/404 ; A61K31/336 ; C07D413/12 ; C07D417/12 ; C07D405/12 ; C07D303/38
摘要：
One aspect of the invention relates to inhibitors that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the treatment of immune related diseases, comprising administering a compound of the invention. In certain embodiments, the invention relates to the treatment of cancer, comprising administering a compound of the invention.
公开/授权文献
- US20120088762A1 COMPOUNDS FOR ENZYME INHIBITION 公开/授权日：2012-04-12
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