- 专利标题： 2,4-pyrimidinediamine compounds and their uses
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申请号： US12273357申请日： 2008-11-18
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公开(公告)号： US08334296B2公开(公告)日： 2012-12-18
- 发明人: Rajinder Singh , Ankush Argade , Donald G Payan , Susan Molineaux , Sasha J Holland , Jeffrey Clough , Holger Keim , Somasekhar Bhamidipati , Catherine Sylvain , Hui Li , Alexander B Rossi
- 申请人： Rajinder Singh , Ankush Argade , Donald G Payan , Susan Molineaux , Sasha J Holland , Jeffrey Clough , Holger Keim , Somasekhar Bhamidipati , Catherine Sylvain , Hui Li , Alexander B Rossi
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 代理商 Travis Young
- 主分类号： A01N43/54
- IPC分类号： A01N43/54 ; A61K31/505 ; C07D239/02
摘要：
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.
公开/授权文献
- US20090156622A1 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES 公开/授权日：2009-06-18
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