Invention Grant
- Patent Title: Kallikrein 7 modulators
- Patent Title (中): 激肽释放酶7调节剂
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Application No.: US12665892Application Date: 2008-06-26
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Publication No.: US08309596B2Publication Date: 2012-11-13
- Inventor: Stefanie Flohr , Stefan Andreas Randl , Nils Ostermann , Ulrich Hassiepen , Frederic Berst , Ursula Bodendorf , Bernd Gerhartz , Andreas Marzinzik , Claus Ehrhardt , Josef Gottfried Meingassner
- Applicant: Stefanie Flohr , Stefan Andreas Randl , Nils Ostermann , Ulrich Hassiepen , Frederic Berst , Ursula Bodendorf , Bernd Gerhartz , Andreas Marzinzik , Claus Ehrhardt , Josef Gottfried Meingassner
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent John B. Alexander
- Priority: EP07111316 20070628; EP07115197 20070829
- International Application: PCT/EP2008/058139 WO 20080626
- International Announcement: WO2009/000878 WO 20081231
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/496 ; A61K31/454 ; A61K31/437 ; A61K31/4375 ; A61K31/404 ; A61K31/4035 ; A61K31/403 ; A61K31/4025 ; A61K31/40 ; C07D413/12 ; C07D409/12 ; C07D405/12 ; C07D401/12 ; C07D403/12 ; C07D217/26 ; C07D211/60 ; C07D209/42 ; C07D209/44 ; C07D209/52 ; C07D207/16
Abstract:
The present invention relates to the crystal structure of the serine protease kallikrein 7 and to the use of this crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7.
Public/Granted literature
- US20100256144A1 Kallikrein 7 modulators Public/Granted day:2010-10-07
Information query
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